A prospective study of rollerball endometrial ablation in the management of refractory recurrent symptomatic endometrial hyperplasia without atypia.
نویسندگان
چکیده
BACKGROUNDS Menorrhagia - heavy, extended or irregular menstruations - may be associated with endometrial hyperplasia. The aim of this study was to evaluate the clinical efficacy and safety of transcervical rollerball endometrial ablation (EA-R) and to discuss surgical outcomes in patients with simple endometrial hyperplasia without atypia who have had a history of medical treatment failure or recurrence. METHODS A prospective study was designed. Thirty women underwent EA-R. Preoperative and postoperative menstrual status, sexual activity, and satisfaction with the procedure were assessed. Complications, clinical outcomes, and need for re-intervention were evaluated. RESULTS No major complications occurred. All patients were discharged from hospital within 24 h. A reduction of menorrhagia was observed in patients as follows: 17 patients (56.67%) had amenorrhea, 10 (33.33%) hypomenorrhea, and 2 (6.67%) eumenorrhea. Hysterectomy was performed only in 1 patient who was unresponsive to ablation treatment. CONCLUSIONS In selected patients who have persistent uterine bleeding not responsive to conservative therapy, low risk for future endometrial cancer, and wish to retain their uterus, EA-R treatment is safe, effective, and might be an alternative to hysterectomy with good toleration and high rate of patient satisfaction. The advantages of EA-R include low incidence of complications, lower morbidity, shorter hospitalization, and faster recovery.
منابع مشابه
RANDOMIZED TRIAL COMPARING ROLLERBALL ABLATION WITH CUTTING LOOP ENDOMETRIAL RESECTION IN THE TREATMENT OF MENORRHAGIA
In order to compare the clinical efficacy, safety, success rate and probable complications of rollerball ablation with cutting loop endometrial resection in the treatment of menorrhagia, eighty-three women in reproductive age suffering from menorrhagia who did not respond to medication were treated in a randomized study comparing cutting loop endometrial resection with hysteroscopic rollerb...
متن کاملبررسی ایمونوهیستوشیمی بروز گیرندههای استروژن و پروژسترون در انواع هیپرپلازی و کارسینوم آندومتریویید آندومتر
Background: Endometrial carcinoma (EC) is the most common gynecologic malignancy however, mechanisms underlying its pathogenesis remain obscure. Endometrial carcinoma has been classified into two major categories: type I (related to estrogen or endometrioid adenocarcinoma) and type II (unrelated to estrogen). Estrogen is the main trigger for the abnormal proliferation in the endometrial epithel...
متن کاملCLINICAL EFFICACY OF HYSTEROSCOPIC ENDOMETRI AL ABLATION AND FACTORS AFFECTING ITS SUCCESS
In order to assess the efficacy of hysteroscopic endometrial ablation and factors which are important in it's success, a prospective, randomized study was performed in Shiraz university hospitals between Sep. 1995 to Feb. 1998. 50 patients with chief complaints of menorrhagia that were in reproductive age (25- 50 years) and had shown no response to medication and D&C underwent endometrial ...
متن کاملAlteration of the K-Ras Gene Expression in Atypical and Nonatypical Hyperplastic Endometrium
BACKGROUND Endometrial cancer is the most common gynecologic malignancy that has often proceeded by a premalignant phase. Modern molecular and immunostaining methods for precancerous lesions diagnosis have been expanded. One of the genetic alternations in the endometrial cancer carcinogenesis is the mutational activation of the K-ras oncogene. K-ras mutation has recognized to occur at an early ...
متن کاملPremalignant and malignant lesions in endometrial polyps in patients undergoing hysteroscopic polypectomy
OBJECTIVE To evaluate the incidence of premalignant lesions and cancer in endometrial polyps, in patients undergoing hysteroscopic polypectomy. METHODS The results of 1,020 pathological examinations of patients submitted to hysteroscopic polypectomy were analyzed, as well as their diagnostic and surgical hysteroscopy findings. As to their menstrual status, 295 (28.9%) patients were in menacme...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Gynecologic and obstetric investigation
دوره 74 4 شماره
صفحات -
تاریخ انتشار 2012